In a small bowl, combine cookie crumbs and butter, mix well. Press onto the bottom and 2 inches up the sides of a greased 9-in. springform pan and set aside.
In a mixing bowl, beat cream cheese and sugar until smooth. Add eggs, beat on low until just combined. Add lemon juice and vanilla, beat until just blended. Pour into crust.
Bake at 350 degrees for 35-40 minutes or until center is almost set. Cool on wire rack of 10 mins. Run a knife around the edge of pan to loosen. Let cool for another hour.